Greater Peoria Metro Area, IL

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How Does CBD Work?


Submitted by Jack Davis, owner of Your CBD Store – Peoria IL

If you missed last month’s article, here are some quick facts about what CBD is:

  • CBD is a cannabinoid
  • Your body produces its own cannabinoids
  • Anandamide is one cannabinoid made by your body
  • Your body has an endocannabinoid system
  • THC and CBD are not the same thing
  • CBD produces no high of any sort
  • CBD is NOT a drug, it’s more like a supplement
  • If someone takes too much CBD, they typically get tired or sleepy
  • No two people are alike, so what works for one may not work for another
  • It often takes experimentation to find the right combination for you
  • Per the 2018 Farm Bill, CBD is legal to grow, process, and sell—as long as it come from the hemp plant and contains less than 0.3% THC.

CBD Receptors:
First, let’s take a quick look at endocannabinoid receptors:

  • CB1 receptors were discovered in 1988 at St Louis Medical University
  • CB1 receptors are connected to the brain and central nervous system
  • CB2 receptors were discovered in 1996 at Hebrew University in Jerusalem
  • CB2 receptors are connected to muscles and organs
  • CB2 receptors are associated with the immune system
  • Below is a graphic to help you understand receptors a bit better

So Just How Does CBD Work?
CBD works as an inhibitor for the CB1 and CB2 receptors. It does so by plugging into receptor ports where pain and/or anxiety signals would be received from various parts of the body. That means that as it attaches to the receptor ports, it could potentially block pain and/or anxiety.

If you think about a child’s toy where they match shapes to holes, this is the same idea. A pain receptor port might be “square” and an anxiety port might be “round.” So we are looking at the age old problem of fitting a square peg in a round hole—in a very figurative sense.

We understand that everyone is different. CBD results vary from person to person. For that matter, aspirin has varying results from person to person, too. Our chemical makeup and metabolism have a lot of influence for how effective CBD is. After all, since aspirin and other pain killers do not work the same for everyone, we can see that this variability is common across all sorts of drugs and supplements.

Who Should Not Take CBD?
It’s always a good idea to speak with your doctor before trying CBD. From a study on Epidiolex alone, those who take these medications may experience increased side effects if CBD is used with:

  • Antidepressants
  • Medications that can cause drowsiness
  • Macrolide antibiotics (erythromycin, clarithromycin, etc.)
  • Heart medications (some calcium channel blockers)

Look for more information on CBD at Have more questions? Reach out to us at Your CBD Store, 4410 N Knoxville Ave, Suite A, Peoria IL 61614. You can call us at 309-569-1908 or email us at